"Hypertrophic cardiomyopathy (HCM). It is a disease in which the heart muscle (myocardium) becomes abnormally thick (hypertrophied). The thickened heart muscle can make it harder for the heart to pump blood. In addition, HCM also causes disruptions of the electrical functions of the heart." Dr. Hidalgo explained as he showed me some illustrations from her test results. "HCM is most commonly due to a mutation in one of nine sarcomeric that results in a mutated protein in the sarcomere, the primary component of the myocyte (the muscle cell of the heart). These are predominantly single-point missense mutations in the genes for beta-myosin heavy chain (MHC), myosin-binding protein C, cardiac troponinT, or tropomyosin. These mutations cause myofibril and myocyte structural abnormalities and pos
