The Unfinished Manuscript is about a man by the name of Frank Salisbury. He is a bestselling mystery novelist. He is also a very controversial man who lives in New York City with his husband and writes about racial injustice that hits too close to home for certain politicians. When he mysteriously disappears while he's working on his book about a man who assassinates the president of the United States, those close to him wonder who might be behind it.