Hundreds of years after a brutal nuclear war wipes out most of humanity, only one mega-city remains: Beacon. With millions of residents and dozens of sprawling districts, it is controlled by The Empress, a seemingly immortal woman who created it from the ashes of the old world. But, behind her and her royal court, the city is really run by a vast network of criminal families known as The 14 Tribes. Vicky De Santos and Luke Thompson belong to one of those families. Vicky's aunt Sunny is the head of the Morrella family, and when she and Luke aren't running a nightclub to sell drugs and launder money for her, they're taking care of any unwanted thorns in Sunny's side. Unfortunately, taking care of one of those thorns sets in motion a series of events that would change all of their lives forever.