With no memories of his past nor his personality, Jackson (a name later given to him) did not think his life could get more miserable until he finds out he is in a world of plagues, with his plague being an inferno. After an attempt to escape from his newly found accommodators, he realizes they (plagued humans) are nothing but outcasts to the outside world and that they are multiple forces planning for their extinction. Left with no choice, Jackson and his comrades fully accept and execute their purpose which is destruction until Jackson's encounter with a certain someone changes them and history.