A genius boy with a psychological instability. A girl who cannot feel fear. A boy who can remember everything without a single flick of effort; and A girl who is unable to feel pain due to a certain condition. Four teenagers with bizarre traits will converge because of a common goal; to unveil the chilling mysteries inside their school. Secrets... Conspiracy... Revelations... Join them to their journey as they try to seize the odds.

Exitiale Septem terrorized the vast population of Metro Manila 9 years ago and after a couple of years, the disease have been successfully contained. The fright and grief it caused have been slowly forgotten and eventually became a mere piece of the distant past. But the dreadful memories is soon to haunt the present as the secrets of the past silently found its way to Arylle Zullein Andino, daughter of the two scientists who lead the project of concocting the cure for the epidemic. As she unravel the mysteries of the pasts, more of it is soon to come. A battle of darkness... A war of love... A riddle of life and annihilation... Arylle is willing to face the true forces of evil by being... A Beautiful Monster.